This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrin…
This book presents some of the latest applications of new theories based on the concept of paraconsistency and correlated topics in informatics, such as pattern recognition (bioinformatics), robotics, decision-making themes, and sample size. Each chapter is self-contained, and an introductory chapter covering the logic theoretical basis is also included. The aim of the text is twofold: to serve…
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Polluted air and contaminated food and water are major causes of human health deterioration, but public health policy has long struggled to effectively address these concerns. This timely book--written for a wide audience of policy makers, researchers, and general readers--synthesizes what we already know about environmental hazards, identifies the gaps in our knowledge, and provides a roadmap …
This book constitutes the refereed proceedings of the 15th International Conference on Web Engineering, ICWE 2015, held in Rotterdam, The Netherlands, in June 2015. The 26 full research papers, 11 short papers, 7 industry papers, 11 demonstrations, 6 posters and 4 contributions to the PhD symposium presented were carefully reviewed and selected from 100 submissions. Moreover 2 tutorials are …
n this book, leading experts provide detailed descriptions of the exciting treatments that are expected to become part of the ophthalmologist’s arsenal within the next 10–20 years. The treatments discussed relate to a wide variety of conditions, including macular degeneration, Leber’s congenital amaurosis, retinitis pigmentosa, choroideremia, and retinoschisis. The authors explain clearly…
This book explains for readers how 3D chip stacks promise to increase the level of on-chip integration, and to design new heterogeneous semiconductor devices that combine chips of different integration technologies (incl. sensors) in a single package of the smallest possible size. The authors focus on heterogeneous 3D integration, addressing some of the most important challenges in this emergi…
Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next generation sequencing technologies, together with novel and ever evolving distinct types of omics data technologies, have put an increasingly complex set of challenges f…
This monograph introduces a numerical computational methodology for thermal performance modeling of cross-flow heat exchangers, with applications in chemical, refrigeration and automobile industries. This methodology allows obtaining effectiveness-number of transfer units (e-NTU) data and has been used for simulating several standard and complex flow arrangements configurations of cross-flow he…
Is there an option to oppose without automatically participating in the opposed? This volume explores different perspectives on dissent, understanding practices, cultures, and theories of resistance, dispute, and opposition as inherently participative. It discusses aspects of the body as a political instance, the identity and subjectivity building of individuals and groups, (micro-)practices of…