This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O2 pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP…
Physical Geography
This open access book collects ten essays that look at intra-regional migration in the Southern Balkans from the late Ottoman period to the present. It examines forced as well as voluntary migrations and places these movements within their historical context, including ethnic cleansing, population exchanges, and demographic engineering in the service of nation-building as well as more recent la…
The two-volume set LNCS 9366 and 9367 constitutes the refereed proceedings of the 14th International Semantic Web Conference, ISWC 2015, held in Bethlehem, PA, USA, in October 2015. The International Semantic Web Conference is the premier forum for Semantic Web research, where cutting edge scientific results and technological innovations are presented, where problems and solutions are discus…
This book focuses on the creation of space as an activity. The argument draws not only on aspects of movement in time, but also on a cultural and specifically social context influencing the creation of the spatial habitus. The book reconsiders existing theories of time and space in the field of urban planning and develops an updated account of spatial activity, experience and space-making. Rece…
Using the domain of crisis management, Christian Reuter explores challenges and opportunities for technology design in emergent environments. He therefore empirically analyzes collaborative work in inter-organizational crisis – such as the police, fire departments, energy network operators and citizens – in order to identify collaboration practices that reveal work infrastructure limitat…
In this book, pioneers and distinguished masters of surgery describe novel minimally invasive colo- and anorectal procedures that have been developed in Asia but are of international applicability. The presented techniques are wide ranging in nature and relate to colon surgery, rectal surgery and the treatment of hemorrhoids, fistulas and chronic constipation. Each procedure is carefully descri…
This book presents the proceedings of Positivity VII, held from 22-26 July 2013, in Leiden, the Netherlands. Positivity is the mathematical field concerned with ordered structures and their applications in the broadest sense of the word. A biyearly series of conferences is devoted to presenting the latest developments in this lively and growing discipline. The lectures at the conference covered…
This volume presents an eclectic mix of original research articles in areas covering the analysis of ordered data, stochastic modeling and biostatistics. These areas were featured in a conference held at the University of Texas at Dallas from March 7 to 9, 2014 in honor of Professor H. N. Nagaraja’s 60th birthday and his distinguished contributions to statistics. The articles were written by …
For Microelectromechanical Systems (MEMS) and Nanoelectromechanical Systems (NEMS) production, each product requires a unique process technology. This book provides a comprehensive insight into the tools necessary for fabricating MEMS/NEMS and the process technologies applied. Besides, it describes enabling technologies which are necessary for a successful production, i.e., wafer planarization …