This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by imp…
This book has following unique features that distinguish it from other works from the same area: 1) Investigates the influence of fissure geometry on strength failure and crack evolution behaviour of real rock material; 2) Analyzes the effect of pre-experiment high-temperature treatment on fracture mechanical behaviour of rock material with a single fissure or two parallel fissures; 3) Compares…
This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.
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This thesis investigates the connection between environmental regulation, technological innovation, and export competitiveness in renewable energy equipment based on a large sample of 225 developed and developing countries from 1990 to 2012. The empirical analysis yields strong supporting evidence for the narrowly strong Porter Hypothesis as well as for the lead market theory. The results sugge…
This book is a treatise on microbial ecology that covers traditional and cutting-edge issues in the ecology of microbes in the biosphere. It emphasizes on study tools, microbial taxonomy and the fundamentals of microbial activities and interactions within their communities and environment as well as on the related food web dynamics and biogeochemical cycling. The work exceeds the traditional do…
This book focuses on the reciprocal interactions between pain, emotion and cognition. International experts report on their findings, clinical experience and the most recent literature on the complex relations between these three domains. Clinical, psychological, behavioral and neuroimaging approaches converge towards aiding patients suffering from pain, cognitive impairment or emotional distre…
This comprehensive book covers the knowledge needed to diagnosis and treat patients with acute and chronic pain. Sections dedicated to patient evaluation, medication management, treating patients with more complex circumstances and interventional management provide clinically-relevant information on an array of topics relevant to both the generalist and specialist. Some sections being organized…
This book deals with recent advances in coastal marine environmental management and governance. Various chapters consider new aspects of conservation, assessment of ecosystem health status, environmental survey and protection, frameworks of ocean service and governance, new applications of geo processing and GIS technology, beach management, aquaculture site selection, assessment of water quali…
This book introduces high power semiconductor laser packaging design. The challenges of the design and various packaging and testing techniques are detailed by the authors. New technologies and current applications are described in detail.