The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
This biography sheds light on all facets of the life and the achievements of Ernst Zermelo (1871-1953). Zermelo is best-known for the statement of the axiom of choice and his axiomatization of set theory. However, he also worked in applied mathematics and mathematical physics. His dissertation, for example, promoted the calculus of variations, and he created the pivotal method in the theory of …
The book covers the most crucial parts of real-time hyperspectral image processing: causality and real-time capability. Recently, two new concepts of real time hyperspectral image processing, Progressive HyperSpectral Imaging (PHSI) and Recursive HyperSpectral Imaging (RHSI). Both of these can be used to design algorithms and also form an integral part of real time hyperpsectral image processin…
This work presents modern implementations of relevant molecular dynamics algorithms using ls1 mardyn, a simulation program for engineering applications. The text focuses strictly on HPC-related aspects, covering implementation on HPC architectures, taking Intel Xeon and Intel Xeon Phi clusters as representatives of current platforms. The work describes distributed and shared-memory parallelizat…
This monograph provides a field-proven approach to analyze industrial production with a cross-company scope as well as regarding all hierarchical system levels of manufacturing enterprises. The book exemplifies this approach in the context of aluminum die casting, and presents a set of measures which allow a 30 percent energy reduction along the value chain. The target audience primarily compri…
The purpose of these notes is to provide an introduction to the Malliavin calculus and its recent application to quantitative results in normal approximations, in combination with Stein’s method. The basic differential operators of the Malliavin calculus and their main properties are presented. We explain the connection of these operators with the Wiener chaos expansion and the Ornstein-Uh…
Knowledge in the field of parasitology must be kept at a high level and up to date in order to fight a parasitosis as quickly and effectively as possible. This work, one of Springer's renowned and authoritative Major Reference Works, contributes to these goals in several ways. First, it comprises a number of entries, consisting of both in-depth essays and definitions. Secondly, the content has …
This is an up-to-date, comprehensive review of the neuropsychiatry of patients with movement disorders, i.e. Parkinson’s disease, Huntington’s disease, dystonia and others, by active authorities in the field, with an emphasis on diagnostic and management issues. This book includes critical appraisal of the methodological aspects and limitations of the current research on the neuropsychia…
This book sheds new light on the use of nanoparticles in the fields of parasitology and public and animal health. Nanotechnology has been used in many fields of research and in practical applications. A special subgroup is represented by the so-called nanobiotechnology, which is a multidisciplinary integration of biotechnology, nanotechnology, chemical processing, material science and engine…
This book presents a systematic study of multivariate wavelet frames with matrix dilation, in particular, orthogonal and bi-orthogonal bases, which are a special case of frames. Further, it provides algorithmic methods for the construction of dual and tight wavelet frames with a desirable approximation order, namely compactly supported wavelet frames, which are commonly required by engineers. I…