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Found 1 from your keywords: author="Jordan, Bénédicte F....
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Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Ca…
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Jordan, Bénédicte F.

Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While normal tissue oxygenation is around 40 mm Hg, both rodent and human tumors possess regions of tissue …

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