The Global Financial Crisis (2007–2009) and the following European Sovereign Debt Crisis (2009–) have caused tremendous changes in the business, economy and governance. The spillover effect and globalization of the crisis affected millions and stated a genuine challenge for modern societies. Thus it was a task of extreme importance for us to revise our book and present actualized resear…
Common properties are shared by NO, H2S and CO: they are beneficial at low concentrations but hazardous in higher amounts; they are small molecules of gas; they can freely cross cell membranes; their effects do not rely on receptors; they are generated enzymatically and their production is regulated; their functions can be mimicked by exogenous application; and their cellular effects may or may…
The first edition of this book has received a very warm reception. A number of instructors have adopted this work as a textbook in their courses. Moreover, both novices and seasoned professionals have been using the book for selfstudy. The enthusiastic response to the book motivated a new edition. One major change is that there are now two authors. The second edition improves the book in se…
This book covers three fundamental problems at the interface of multi-project management and human resource management: the selection of projects, the composition of small project teams, and workload leveling. Matthias Walter proposes optimization models and solution methods for these problems, assuming multi-skilled workers with heterogeneous skill levels. For the first time, the author presen…
This book takes a concentrated look at the very latest best practices for Office 365 migration, with a focus on the needs of senior managers, IT managers, and others involved in key decisions when moving their business to the cloud. Based on popular chapters in his first book, Office 365: Migrating and Managing Your Business in the Cloud (Apress Open, co-authored with Don Crawford), author M…
This book describes the three gasotransmitters nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO) and their function as intracellular signalling molecules in plants. Common properties are shared by NO, H2S and CO: they are beneficial at low concentrations but hazardous in higher amounts; they are small molecules of gas; they can freely cross cell membranes; their effects do …
This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. Special emphasis is given to already established and emerging molecular diagnostic tests in neuropathology, as well as molecular targeted therapies. The book is organized by clinico-pathologic d…
This book offers readers a snapshot of the progression of molecular modeling in the electronics industry and how molecular modeling is currently being used to understand materials to solve relevant issues in this field. The reader is introduced to the evolving role of molecular modeling, especially seen from the perspective of the IEEE community and modeling in electronics. This book also cover…
Controlled radical polymerization techniques for molecular imprinting, by Mark E. Byrne From bulk polymers to nanoparticles, by Lei Ye Post-imprinting and in-cavity functionalization, by Toshifumi Takeuchi Characterization of MIPs (affinity, selectivity, site heterogeneity…), by Richard Ansell Theoretical aspects and computer modelling, by Ian Nicholls MIPs in aqueous environments, by Bi…
Presenting a study of geometric action functionals (i.e., non-negative functionals on the space of unparameterized oriented rectifiable curves), this monograph focuses on the subclass of those functionals whose local action is a degenerate type of Finsler metric that may vanish in certain directions, allowing for curves with positive Euclidean length but with zero action. For such functionals, …