This book constitutes the refereed proceedings of the 15th European Conference on Evolutionary Computation in Combinatorial Optimization, EvoCOP 2015, held in Copenhagen, Denmark, in April 2015, co-located with the Evo*2015 events EuroGP, EvoMUSART and EvoApplications. The 19 revised full papers presented were carefully reviewed and selected from 46 submissions. The papers cover methodology,…