This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulatio…
The theory of Schur–Weyl duality has had a profound influence over many areas of algebra and combinatorics. This text is original in two respects: it discusses affine q-Schur algebras and presents an algebraic, as opposed to geometric, approach to affine quantum Schur–Weyl theory. To begin, various algebraic structures are discussed, including double Ringel–Hall algebras of cyclic quivers…
Ilmu pengetahuan hayati berkembang pesat setiap harinya. Peningkatan genomik dan teknik analisis terkait sangat mendorong perkembangan pesat transkriptomik, proteomik, metabolomik, dan fenomenik. Dengan demikian, sarana integrasi sistem dapat digunakan untuk mengungkapkan fenomena kehidupan di berbagai tingkatan. Pemikiran dan metode penelitian di atas melahirkan biologi sistem. Metabolomik mer…
Biopatents frequently disclose sequences of polypeptides and nucleic acids in the written description. The claims often cover a homology range surrounding the disclosed sequence to get a broader protection. However, homology claims face a hurdle that they may lack support by the written description. The Supreme Court of China ruled that homology claims lack support, but a further limitation by …
This book is a systematic summary of some new advances in the area of nonlinear analysis and design in the frequency domain, focusing on the application oriented theory and methods based on the GFRF concept, which is mainly done by the author in the past 8 years. The main results are formulated uniformly with a parametric characteristic approach, which provides a convenient and novel insight in…
This book provides an overview of circadian rhythms and cellular networks in their relation to biological systems and dynamical medicine. Six concise chapters explore circadian cell rhythms and biomarkers in inflammation, cardiovascular disease, cancer, depression, and more in causing and treating these ailments. The final chapter discusses optimization of drug delivery and individualized treat…
This study describes the fundamentals of assessing the vulnerability of coral islands, as well as environmental management and resource exploitation. Using seabird subfossils, such as bones, guano, eggshells etc., which have been well preserved on the Xisha Islands in the South China Sea, the author identifies the influences of climate change and human activity on seabird populations and diets.…
The present book provides guidance to understanding complicated coupled processes based on the experimental data available and implementation of developed algorithms in numerical codes. Results of selected test cases in the fields of closed-form solutions (e.g., deformation processes), single processes (such as groundwater flow) as well as coupled processes are presented. It is part of the O…
Active technological development has fuelled rapid growth in the number of Unmanned Aerial Vehicle (UAV) platforms being deployed around the globe. Novel UAV platforms, UAV-based sensors, robotic sensing and imaging techniques, the development of processing workflows, as well as the capacity of ultra-high temporal and spatial resolution data, provide both opportunities and challenges that will …
This book provides a comprehensive set of optimization and prediction techniques for an enterprise information system. Readers with a background in operations research, system engineering, statistics, or data analytics can use this book as a reference to derive insight from data and use this knowledge as guidance for production management. The authors identify the key challenges in enterprise i…