The second volume of the Special Issue entitled “Antimicrobial Prescribing and Stewardship” consists of manuscripts, including original research articles, review articles, and opinion papers regarding antimicrobial stewardship-related topics, including disease-based/organism-based antimicrobial stewardship; the influence of antimicrobial utilization changes on antimicrobial resistance; the …
The Pacific Trade and Development (PAFTAD) conference series has been at the forefront of analysing challenges facing the economies of East Asia and the Pacific since its first meeting in Tokyo in January 1968. The 38th PAFTAD conference met at a key time to consider international economic integration. Earlier in the year, the people of the United Kingdom voted to leave the European Union and t…
This e-book focuses primarily on the role of the fornix as a functional, prognostic, and diagnostic marker of Alzheimer's disease (AD), and the application of such a marker in clinical practice. Researchers have long been focused on the cortical pathology of AD, since the most important pathologic features are the senile plaques found in the cortex, and the neurofibrillary tangles and neuronal …
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researcher…
Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modification such as methylation of histone H3 lysine 9 (H3K9) and tri-methylation of H3K27. MiRNAs are smal…
Edisi kelima dari PULP Guide merupakan instrumen referensi esensial yang dirancang untuk membantu akademisi hukum, peneliti, dan praktisi dalam menavigasi lanskap publikasi ilmiah yang semakin kompleks. Buku panduan ini menyajikan daftar komprehensif jurnal hukum, baik di tingkat regional (khususnya Afrika) maupun internasional, yang telah diakreditasi dan diakui secara luas. Fokus utama edisi …
Karya digital yang inovatif ini mengundang pembaca untuk membayangkan Islam secara baru. Melampaui pendekatan teologis, nativis, dan orientalis konvensional, Shahzad Bashir melepaskan Islam dari identifikasi geografis dengan Timur Tengah, artikulasi melalui otoritas laki-laki saja, dan asumsi bahwa ekspresi pramodern lebih otentik Islami daripada yang modern. Berfokus pada waktu sebagai konstru…
Green tea (GT) contains well-known phytochemical compounds; namely, it is rich in flavan-3-ols (catechins) and flavonols comprising all glycoside forms. These compounds in GT might show better biological activities after a feasible enzymatic process, and the process on an industrial scale should consider enzyme specificity and cost-effectiveness.
Fungi are a prolific source of bioactive molecules. During the past few decades, many bioactive natural products have been isolated from marine fungi. Chile is a country with 6435 Km of coastline along the Pacific Ocean and houses a unique fungal biodiversity. This review summarizes the field of fungal natural products isolated from Antarctic and Chilean marine environments and their biolog…
Exploration for specialized metabolites of Okinawan marine sponges Agelas spp. resulted in the isolation of five new bromopyrrole alkaloids, agesasines A (1) and B (2), 9-hydroxydihydrodispacamide (3), 9-hydroxydihydrooroidin (4), and 9E-keramadine (5). Their structures were elucidated on the basis of spectroscopic analyses. Agesasines A (1) and B (2) were assigned as rare bromopyrrole alka…