This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functio…
The last decade has witnessed significant progress in understanding the organization and regulation of regenerative cells in the adult lung. The development and refinement of multiparameter flow cytometric cell sorting protocols and in vitro clonogenic assays has enabled the identification, prospective isolation, and characterization of candidate adult lung stem and progenitor cells. Powerful…