The volume presents, in a synergistic manner, significant theoretical and practical contributions in the area of social media reputation and authorship measurement, visualization, and modeling. The book justifies and proposes contributions to a future agenda for understanding the requirements for making social media authorship more transparent. Building on work presented in a previous volume of…
The calculation of channel capacities was one of Rudolf Ahlswede's specialties and is the main topic of this second volume of his Lectures on Information Theory. Here we find a detailed account of some very classical material from the early days of Information Theory, including developments from the USA, Russia, Hungary and (which Ahlswede was probably in a unique position to describe) the Germ…
Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and poten…
This book provides a comprehensive review of the latest advances in translational pain and itch research, and presents the cutting-edge developments in the study of our two principal, yet most mysteries sensations. Despite the slow progress in the discovery of effective therapies for chronic pain and pruritus, scientists around the globe now have a better understanding of why and how these cond…
Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Mos…
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin …
Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology,…
This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importa…
Networks are everywhere: networks of friends, transportation networks and the Web. Neurons in our brains and proteins within our bodies form networks that determine our intelligence and survival. This modern, accessible textbook introduces the basics of network science for a wide range of job sectors from management to marketing, from biology to engineering, and from neuroscience to the social …
GNU / Linux (https://www.gnu.org/gnu/linux-and-gnu.html) adalah blok bangunan dasar Internet. Banyak situs Internet yang paling banyak dikunjungi menjalankan beberapa rasa GNU / Linux. Bersama dengan GNU / Linux adalah perangkat lunak bebas dan sumber terbuka lainnya yang digunakan untuk membangun infrastruktur bagi organisasi. Buku ini berfungsi sebagai panduan bagi para insinyur yang ingin me…