This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections: · Evolution and detection of endogenous ADP-ribosylation · ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs) · ADP-ribosylation by the ARTD family of ADP-ribosyltransfe…
What do stories in games have in common with political narratives?This book identifies narrative strategies as mechanisms for meaning and manipulation in games and real life. It shows that the narrative mechanics so clearly identifiable in games are increasingly used (and abused) in politics and social life. They have »many faces«, displays and interfaces. They occur as texts, recipes, storie…
The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelopoiesis is perturbed and instead of generating immunogenic myeloid cells (such as dendritic cells,…
This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also …
This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also …
As most industrialised countries, Switzerland is increasingly attempting to (re)integrate people with health restrictions and disabilities into the job market. The reinforced political demand to reintegrate people with health restrictions challenges both the involved organisations and its employees. While the means and methods to assess (in)capacity for work are more and more refined, the accor…
Treatments for Eating Disorders: The Patients' Views
With the rise of the ‘knowledge for development’ paradigm, expert advice has become a prime instrument of foreign aid. At the same time, it has been object of repeated criticism: the chronic failure of ‘technical assistance’ – a notion under which advice is commonly subsumed – has been documented in a host of studies. Nonetheless, international organisations continue to send advisor…
Why do we play games and why do we play them on computers? The contributors of »Games and Rules« take a closer look at the core of each game and the motivational system that is the game mechanics. Games are control circuits that organize the game world with their (joint) players and establish motivations in a dedicated space, a »Magic Circle«, whereas game mechanics are constructs o…
In this bold and original study, Jeff Kochan constructively combines the sociology of scientific knowledge (SSK) with Martin Heidegger’s early existential conception of science. Kochan shows convincingly that these apparently quite different approaches to science are, in fact, largely compatible, even mutually reinforcing.