This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-a…
Calculus was first developed more than three hundred years ago by Sir Isaac Newton and Gottfried Leibniz to help them describe and understand the rules overning the motion of planets and moons. Since then, thousands of other men and women have refined the basic ideas of calculus, developed new techniques to make the calculations easier, and found ways to apply calculus to problems besides plane…
This book has been created to help you make decisions about practical conservation management by providing an assessment, from the available scientific evidence, of what works and what does not work in conservation. It also tells you if no evidence has been found about whether or not a conservation intervention is effective. This is the 2017 edition of What Works in Conservation, which was fir…
The purpose of these books is to have an updated systematic overview examining, in detail, the functional role of different diets and dietary components in maintaining glucose homeostasis and preventing long-term complications. The first book includes experimental evidence from preclinical research, whereas the second book provides studies in the clinical scenario.
The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coff…
Ce recueil puise sa source dans les cours de master de mathématiques appliquées et de préparation à l’épreuve de modélisation de l’agrégation de mathématiques. Le parti pris de cet ouvrage est de polariser la rédaction par les modèles plutôt que par les outils, et de consacrer chaque chapitre à un modèle. Le premier public visé est celui des enseignants-chercheurs en probabili…
This book constitutes the refereed proceedings of the 30th International Conference, ISC High Performance 2015, [formerly known as the International Supercomputing Conference] held in Frankfurt, Germany, in July 2015. The 27 revised full papers presented together with 10 short papers were carefully reviewed and selected from 67 submissions. The papers cover the following topics: cost-efficie…
Financial Risk Measurement is a challenging task, because both the types of risk and the techniques evolve very quickly. This book collects a number of novel contributions to the measurement of financial risk, which address either non-fully explored risks or risk takers, and does so in a wide variety of empirical contexts.
Valvular heart medicine revolves around the need to accurately identify locations of pathological structures and/or the interventional tools needed to manage that pathology. The imaging of the valves is developing at an enormous pace and the clinician must be aware of the advantages of each modality and how it compares to the others available. There is a need for a practical, clinical atlas des…
This volume covers the pathophysiology, epidemiology, presentation, diagnosis, medical and surgical management of benign biliary stenosis. The book is uniquely structured in a way that allows areas of controversy to be highlighted through the use of a two chapter format for each topic. Each chapter topic is written by an expert in the field, with a second expert highlighting controversies and …