The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistan…
This collection is an essential supplement to the recent academic handbooks on children’s rights studies and international children's rights law. Over the years, the international legal framework on children's rights has evolved into a complex system, which includes United Nations treaties and resolutions, regional human rights instruments, such as treaties, recommendations, resolutions, and …
Integration in the empire under the political control of the city of Rome, her princeps, and the different authorities in the provinces and cities includes processes of inclusion and exclusion. These multifaceted processes take place at various levels in society and at different places, over a long period of time. In this volume, these processes are analysed and reflected on from different pers…
One Health addresses health challenges arising from the intertwined spheres of humans, animals and ecosystems. This handbook is the product of an interdisciplinary effort to provide science-based guidance for the evaluation of One Health and other integrated approaches to health. It guides the reader through a systems approach and framework to evaluate such approaches in a standardised way. It …
This book explores how European naturalists and artists perceived, investigated, and presented the relationship between insects and colors from the late sixteenth to the late eighteenth century. The contributors to this volume examine the creative methods and strategies that were developed to record color-related information about insects through studies on Hoefnagel’s glazed metal and hand-c…
This book addresses the conceptualization and practice of Indigenous research methodologies especially in Sámi and North European academic contexts. It examines the meaning of Sámi research and research methodologies, practical levels of doing Indigenous research today in different contexts, as well as global debates in Indigenous research. The contributors present place-specific and relation…