Sven-Michael Wundenberg discusses the development of a reference architecture for the Learning Management System’s (LMS) selection-process aimed at the system’s implementation in a polytechnic-knowledge-transfer organization. The focus lies on the requirement engineering (RE) process’s quintessence based on research about standard RE-procedures and -approaches combined with LMS-basic know…
Healthcare and well-being have captured the attention of established software companies, start-ups, and investors. Software is starting to play a central role for addressing the problems of the aging society and the escalating cost of healthcare services. Enablers of such digital health are a growing number of sensors for sensing the human body and communication infrastructure for remote meetin…
This book focuses on various topics related to engineering and management of requirements, in particular elicitation, negotiation, prioritisation, and documentation (whether with natural languages or with graphical models). The book provides methods and techniques that help to characterise, in a systematic manner, the requirements of the intended engineering system. It was written with the …
This book constitutes the refereed proceedings of the 20th International Working Conference on Requirements Engineering: Foundation for Software Quality, REFSQ 2014, held in Essen, Germany, in April 2013. The 23 papers presented together with 1 keynote were carefully reviewed and selected from 62 submissions. The REFSQ'15 conference is organized as a three-day symposium. The REFSQ'15 has chosen…
This book constitutes the proceedings of the second Asia Pacific Requirements Engineering Symposium, APRES 2015, held in Wuhan, China, in October 2015. The 9 full papers presented together with 3 tool demos papers and one short paper, were carefully reviewed and selected from 18 submissions. The papers deal with various aspects of requirements engineering in the big data era, such as automat…
This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cy…
This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of resistance is a major obstacle in cancer chemotherapy and the field has been moving rapidly in terms o…
This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignan…
This book explains why the climate change crisis is a symptom of a much larger underlying problem – namely, humankind’s predilection with continuous GDP-growth. Given this starting point, the world’s high-income nations must begin the transition to a qualitatively-improving steady-state economy and low-income nations must follow suit at some stage over the next 20-40 years. Unless they do…
This volume studies electron resonant tunneling in two- and three-dimensional quantum waveguides of variable cross-sections in the time-independent approach. Mathematical models are suggested for the resonant tunneling and develop asymptotic and numerical approaches for investigating the models. Also, schemes are presented for several electronics devices based on the phenomenon of resonant t…