This volume develops results on continuous time branching processes and applies them to study rate of tumor growth, extending classic work on the Luria-Delbruck distribution. As a consequence, the author calculate the probability that mutations that confer resistance to treatment are present at detection and quantify the extent of tumor heterogeneity. As applications, the author evaluate ovaria…
This volume provides a comprehensive review of the clinical, radiological and clinical aspects in the disease process. The text provides the general pathologist, clinician and pulmonary pathologist with a framework on how to work up a case of either non-neoplastic or neoplastic lung disease and provide clinically relevant information to all involved in patient care. The basic understanding of r…
Diagnostic Cytopathology Board Review and Self-Assessment provides a comprehensive systems-based review of non-gynecological cytology including cytomorphology, pitfalls and ancillary studies, presented in a high-yield format with board-type multiple choice questions and detailed answers. It provides an excellent review, resource and self-assessment for pathologists, cytopathologists and cytotec…
This is the first volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date…
The new and updated edition of this book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, serving as an introduction to the topic with clear explanations of difficulties and pitfalls. It has been fully revised in light of developments over the past 5 years and includes STARD publications which have appeared since the first edition as well as the use…
Analyzed and implemented in Java, the data structures presented in the book include stacks, queues, deques, and lists implemented as arrays and linked-lists; space-efficient implementations of lists; skip lists; hash tables and hash codes; binary search trees including treaps, scapegoat trees, and red-black trees; integer searching structures including binary tries, x-fast tries, and y-fast tri…
Over the past 20 years, diagnostic tests for pediatric pulmonologists have revolutionized care of children afflicted with respiratory disorders. These tests have been used to not only help in diagnosis, but also in the management and treatment of these children. Bronchoscopic, imaging and physiologic advances have improved clinical care of these children and have been used as outcome measures i…
Intended to introduce readers to the use of artificial neural networks in the study of music, this volume contains numerous case studies and research findings that address problems related to identifying scales, keys, classifying musical chords, and learning jazz chord progressions. A detailed analysis of the internal structure of trained networks could yield important contributions to the fiel…
This book provides a complete overview of significant design challenges in respect to circuit miniaturization and power reduction of the neural recording system, along with circuit topologies, architecture trends, and (post-silicon) circuit optimization algorithms. The introduced novel circuits for signal conditioning, quantization, and classification, as well as system configurations focus on …