This, the first of two volumes on personalized medicine in lung cancer, touches on the core issues related to the understanding of lung cancer—statistics and epidemiology of lung cancer—along with the incidence of lung cancer in non-smokers. A major focus of this volume is the state of current therapies against lung cancer—immune, targeted therapies against EGFR TKIs, KRAS, ALK, angiogene…
Lung cancer and autoimmune diseases are complex entities in that they involve gene disturbance, gene polymorphism, and impaired gene repair mechanisms. The volume focuses on altered gene expression in tumor processes and in chronic autoimmune disorders. The chapters discuss the biological rationale for novel disease protein markers, present relevant clinical results, and give some diagnostic an…
This book provides readers with a clear description of the types of lunar and interplanetary trajectories, and how they influence satellite-system design. The description follows an engineering rather than a mathematical approach and includes many examples of lunar trajectories, based on real missions. It helps readers gain an understanding of the driving subsystems of interplanetary and lunar …
The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecul…
This book highlights the economic relevance of the so-called low-tech industries and firms. Non R&D intensive firms continue to be the economic backbone of several developed industrial countries. They form the core of National Innovation Systems and contribute significantly to growth and employment. However, due to their lack of R&D activity, they are easily overlooked in the general innovation…
This edited book aims at presenting current research activities in the field of robust variable-structure systems. The scope equally comprises highlighting novel methodological aspects as well as presenting the use of variable-structure techniques in industrial applications including their efficient implementation on hardware for real-time control. The target audience primarily comprises resear…
Jan Buchmann focuses on the valuation of a firm’s innovation potential based on that firm’s position in its lifecycle. Compared to existing research, the author does not center his research exclusively on mathematical valuation methodologies. Instead, the author compares collected valuation input data, data interpretation approaches, and valuation methodologies suggested by theory with the …
This book aims to overcome the limitations the variations in bank-specifics impose by providing a bank-specific valuation theoretical framework and a new asset-side model. The book includes also a constructive comparison of equity and asset side methods. The authors present a novel framework entitled, the “Asset Mark-down Model”. This method incorporates an Adjusted Present Value model, whi…
This monograph is the first book-length treatment of valuation theory on finite-dimensional division algebras, a subject of active and substantial research over the last forty years. Its development was spurred in the last decades of the twentieth century by important advances such as Amitsur's construction of non crossed products and Platonov's solution of the Tannaka-Artin problem. This st…
This book is a collection of scholarly articles presenting the research results of work carried out under the supervision of Prof. Saroj Bhosle, a microbiologist at Goa University, India.The objective of this volume is to document the comprehensive ecological knowledge of eubacteria isolated from diverse coastal ecosystems of Goa, little explored for microbiological studies. These ecosystems ne…