The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, …
Drawing on original archival research, A Feminine Enlightenment argues that women writers shaped Enlightenment conversations regarding the role of sentiment and gender in the civilizing process. By reading women's literature alongside history and philosophy and moving between the eighteenth century and Romantic era, JoEllen DeLucia challenges conventional historical and generic boundaries. Begi…
When close to a continuous phase transition, many physical systems can usefully be mapped to ensembles of fluctuating loops, which might represent for example polymer rings, or line defects in a lattice magnet, or worldlines of quantum particles. 'Loop models' provide a unifying geometric language for problems of this kind. This thesis aims to extend this language in two directions. The first p…
This textbook gives a comprehensive overview of the key principles of business marketing. The reader will be introduced into methods and theories in order to understand business markets and marketing better. Not only are the principles of business marketing addressed, but also deep knowledge of organizational buying and market research on business markets. The book sets the stage for develop…
This book presents a comprehensive and systematic introduction to transforming process-oriented data into information about the underlying business process, which is essential for all kinds of decision-making. To that end, the authors develop step-by-step models and analytical tools for obtaining high-quality data structured in such a way that complex analytical tools can be applied. The main e…
This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts fro…
This book aims to cover different aspects of Bias Temperature Instability (BTI). BTI remains as an important reliability concern for CMOS transistors and circuits. Development of BTI resilient technology relies on utilizing artefact-free stress and measurement methods and suitable physics-based models for accurate determination of degradation at end-of-life and understanding the gate insulator …
Acarology - the study of mites and ticks, is a subdiscipline of Zoology, and is many times considered in the field of Entomology (the study of insects). Mites and ticks are distributed throughout the world and inhabit almost every ecosystem (both terrestrial and aquatic) including grassland soils. More than 55,000 species of mites and ticks are already described. Mites and ticks directly affect…
This book provides a comprehensive basics-to-advanced course in an aero-thermal science vital to the design of engines for either type of craft. The text classifies engines powering aircraft and single/multi-stage rockets, and derives performance parameters for both from basic aerodynamics and thermodynamics laws. Each type of engine is analyzed for optimum performance goals, and mission-approp…
This book is an accessible guide to adaptive signal processing methods that equips the reader with advanced theoretical and practical tools for the study and development of circuit structures and provides robust algorithms relevant to a wide variety of application scenarios. Examples include multimodal and multimedia communications, the biological and biomedical fields, economic models, environ…