This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microen…
This two-volume work provides an overview on various state of the art experimental and statistical methods, modeling approaches and software tools that are available to generate, integrate and analyze multi-omics datasets in order to detect biomarkers, genetic markers and potential causal genes for improved animal production and health. The book will contain online resources where additional da…
Psychology, like most other sciences, has its own set of tools to investigate the important research questions of its field. Unlike other sciences, psychology is a relatively new field with methods and practices that are evolving at a rapid rate. With this textbook, we introduce students to the fundamental principles of what it is like to think like a psychology researcher. We also hope to conn…
This widely anticipated book harnesses the dispersed knowledge of international experts who highlight pedagogical, organizational, cultural, social, and economic factors that influence the adoption and integration of emerging technologies in distance education. Emerging Technologies in Distance Education provides expert advice on how educators can launch effective and engaging distance educatio…
This book deals with magnetorheological fluid theory, modeling and applications of automotive magnetorheological dampers. On the theoretical side a review of MR fluid compositions and key factors affecting the characteristics of these fluids is followed by a description of existing applications in the area of vibration isolation and flow-mode shock absorbers in particular. As a majority of exis…
This monograph examines in detail models of neural systems described by delay-differential equations. Each element of the medium (neuron) is an oscillator that generates, in standalone mode, short impulses also known as spikes. The book discusses models of synaptic interaction between neurons, which lead to complex oscillatory modes in the system. In addition, it presents a solution to the prob…
Where institutions and individuals averagely invest the majority of their assets in money-market and fixed-income instruments, interest rate risk management could be seen as the single most important global financial issue. However, the majority of the key techniques used by most investors were developed several decades ago, and the advantages of multi-factor models are not fully recognised by …
Written by leading experts in the field, this edited volume brings together the latest findings in the area of nonparametric, robust and multivariate statistical methods. The individual contributions cover a wide variety of topics ranging from univariate nonparametric methods to robust methods for complex data structures. Some examples from statistical signal processing are also given. The volu…
This textbook offers clear explanations of optical spectroscopic phenomena and shows how spectroscopic techniques are used in modern molecular and cellular biophysics and biochemistry. The topics covered include electronic and vibrational absorption, fluorescence, resonance energy transfer, exciton interactions, circular dichroism, coherence and dephasing, ultrafast pump-probe and photon-echo s…
The author defends nonconceptualism, the claim that perceptual experience is nonconceptual and has nonconceptual content. Continuing the heated and complex debate surrounding this topic over the past two decades, she offers a sustained defense of a novel version of the view, Modest Nonconceptualism, and provides a systematic overview of some of the central controversies in the debate. An expli…