This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current unde…
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system (CNS) and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role i…
After the most recent financial crisis it has become clear that there exists a crisis also in economics as a science. The prevailing paradigms have failed to anticipate and to understand the financial crisis. New approaches are therefore needed. Of particular interest should be approaches that combine insights from those parts of economics that are largely neglected by the mainstream. Hendrik H…
The second decade of the twenty-first century has witnessed a surging interest in personalized medicine with the concomitant promise to enable more precise diagnosis and treatment of disease and illness, based upon an individual’s unique genetic makeup.In this book, my goal is to contribute to a growing body of literature on personalized medicine by tracing and analyzing how this field has bl…
This book weaves together voices of faculty, residents, mentors, administrators, community organizers, and students who have lived together in a third space urban teacher residency program in Newark as they reinvent math and science teaching and teacher education through the lens of inquiry. Each chapter includes narratives from multiple perspectives as well as tools we have used within the pro…
Growing inequalities in Europe are a major challenge threatening the sustainability of urban communities and the competiveness of European cities. While the levels of socio-economic segregation in European cities are still modest compared to some parts of the world, the poor are increasingly concentrating spatially within capital cities across Europe. An overlooked area of research, this book o…
Emphasizing XAML and C#, this book provides readers with all the tools, ideas, and inspiration to begin Windows Universal App development for Windows 10. Real World Windows 10 Development addresses developers who want to break into this market by providing detailed explanations of the various aspects of Universal App development. Written by authors with deep knowledge in Windows 10 universal…
The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the …
This two-volume book explores how the great buildings of England bear witness to a thousand years of the nation’s history. In every age, investment in iconic buildings reaches a climax when the prevailing mode of production is operating most effectively, surplus wealth is most plentiful, and the dominant class rules supreme. During such periods of stability and prosperity, the demand for new …
Data mining applications range from commercial to social domains, with novel applications appearing swiftly; for example, within the context of social networks. The expanding application sphere and social reach of advanced data mining raise pertinent issues of privacy and security. Present-day data mining is a progressive multidisciplinary endeavor. This inter- and multidisciplinary approach is…