This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral syste…
Twenty years after its discovery, recombinant human leptin has been approved by the Food and Drug Administration for the treatment of patients with lipodystrophy. Beginning with a synthesis of the vast body of work on its discovery, dissection of mechanisms, and effects in experimental models , the focus of this book shifts to a consideration of the regulation and role of leptin in humans. The …
This anthology is about the signal change in Leibniz’s metaphysics with his explicit adoption of substantial forms in 1678-79. This change can either be seen as a moment of discontinuity with his metaphysics of maturity or as a moment of continuity, such as a passage to the metaphysics from his last years. Between the end of his sejour at Paris (November 1676) and the first part of the Ha…
This book offers a general introduction to the geometrical studies of Gottfried Wilhelm Leibniz (1646-1716) and his mathematical epistemology. In particular, it focuses on his theory of parallel lines and his attempts to prove the famous Parallel Postulate. Furthermore it explains the role that Leibniz’s work played in the development of non-Euclidean geometry. The first part is an overview o…
The world population will grow more rapidly during the few coming years. This must be accompanied by a parallel increase in the agricultural production to secure adequate food. Sustainability considerations mandate that alternatives to chemical nitrogen fertilizers must be urgently sought. Biological nitrogen (N2) fixation, a microbiological process which converts atmospheric N2 into a plant-us…
This book offers readers a comprehensive and in-depth legal analysis of corporate social responsibility (CSR) by examining the theoretical foundations of corporate governance and its legal mechanism in the United States and South Korea. Moreover, it proposes legislative blueprint for establishing the legal frameworks that might serve to legitimize and effectively implement CSR in general. Refle…
With a foreword by Lewis Cardinal, A Metaphoric Mind brings together for the first time key works selected from among Dr. Joe’s writings, published and unpublished. Spanning nearly thirty years, the essays invite us to share in his transformative legacy through a series of encounters, with Aboriginal spirituality and ancestral ways of knowing, with Elders and their teachings, with education a…
One of the top four contributors to the global burden of disease is diarrheal infections. Intestinal parasites are major causes of morbidity and mortality associated with diarrheal diseases in both the developed and developing world. Amebiasis is responsible for 50 million cases of invasive disease and 70,000 deaths annually in the world. Giardiasis has an estimated worldwide prevalence of 280 …
From Bricks to Brains introduces embodied cognitive science, and illustrates its foundational ideas through the construction and observation of LEGO Mindstorms robots. Discussing the characteristics that distinguish embodied cognitive science from classical cognitive science, From Bricks to Brains places a renewed emphasis on sensing and acting, the importance of embodiment, the exploration of …
Intended to introduce readers to the use of artificial neural networks in the study of music, this volume contains numerous case studies and research findings that address problems related to identifying scales, keys, classifying musical chords, and learning jazz chord progressions. A detailed analysis of the internal structure of trained networks could yield important contributions to the fiel…