This book offers readers a primer on the theory and applications of Ordinary Differential Equations. The style used is simple, yet thorough and rigorous. Each chapter ends with a broad set of exercises that range from the routine to the more challenging and thought-provoking. Solutions to selected exercises can be found at the end of the book. The book contains many interesting examples on topi…
This book provides a chronological introduction to the science of motion and rest based on the reading and analysis of significant portions of Galileo’s Dialogues Concerning Two New Sciences, Pascal’s Treatise on the Equilibrium of Fluids and the Weight of the Mass of Air, Newton’s Mathematical Principles of Natural Philosophy, and Einstein’s Relativity. Each chapter begins with a sh…
This book provides a chronological introduction to the sciences of astronomy and cosmology based on the reading and analysis of significant selections from classic texts, such as Ptolemy’s The Almagest, Kepler’s Epitome of Copernican Astronomy, Shapley’s Galaxies and Lemaître’s The Primeval Atom. Each chapter begins with a short introduction followed by a reading selection. Carefull…
Sets out a simple month-by-month program to reveal all of the night sky's biggest and most beautiful secrets in just one year – and with only a few hours of stargazing each month By investing just an hour a week and $50 in binoculars, it’s possible to learn a few simple techniques and quickly gain a real insight into the night sky's ever-changing patterns – and what they tell us about E…
The second edition of this classic textbook presents a rigorous and self-contained introduction to real analysis with the goal of providing a solid foundation for future coursework and research in applied mathematics. Written in a clear and concise style, it covers all of the necessary subjects as well as those often absent from standard introductory texts. Each chapter features a “Problems…
Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole g…
This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., …
This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text context…
This books discusses the design, electrical simulation and layout of a 2nd-order ∑∆ analog-to-digital converter (ADC), using oxide thin-film transistors (TFTs) technology. The authors provide a unified view of materials science and electronics engineering, in order to guide readers from both fields through key topics. To accomplish this goal, background regarding materials, device physics, …
This book reviews the current state of information on reactive oxygen and nitrogen species and their role in cell communication during plant growth, development and adaptation to stress conditions. It addresses current research advances made in the area of reactive oxygen and nitrogen species (ROS and RNS) signaling. These free radical molecules are important in plant-microbe interactions, r…