This volume presents information on both the basic and clinical aspects of sphingolipid-metabolizing enzymes in various cancers. The volume also includes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel…
This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry. Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediator…
This book summarizes work being pursued in the context of the CIPRNet (Critical Infrastructure Preparedness and Resilience Research Network) research project, co-funded by the European Union under the Seventh Framework Programme (FP7). The project is intended to provide concrete and on-going support to the Critical Infrastructure Protection (CIP) research communities, enhancing their preparedne…
This volume provides a general overview of the therapeutic potential of the essential oils in cancer and highlights some promising future directions. It integrates chemistry, pharmacology, and medicine while discussing bioactive essential oils in experimental models and clinical studies of cancer. The book is a valuable resource for all engaged in the study of natural products and their synthet…
This volume looks at the impact that different cropping systems and tillage have on soil’s biologically active substances. It considers how phytotoxins accumulate and can inhibit the development of cultivated plants. Coverage explores the continuous cropping of rye, crop rotation, no tillage, and conventional tillage. It offers a comprehensive, comparative approach to allelopathic plant-soil …
This fundamental work explains in detail systems for active safety and driver assistance, considering both their structure and their function. These include the well-known standard systems such as Anti-lock braking system (ABS), Electronic Stability Control (ESC) or Adaptive Cruise Control (ACC). But it includes also new systems for protecting collisions protection, for changing the lane, or fo…
Over the last ten years a fresh air has been blowing in the field of molecular magnetism with the re-introduction of lanthanides ions as spin carriers in magnetic molecules. The strong magnetic moment and huge magnetic anisotropy of lanthanide ions has enabled significant breakthroughs in magnetic blocking temperature and related phenomena. The chemical versatility of these ions is also a stron…
This authoritative reference provides comprehensive coverage of the topics of damage and healing mechanics. Computational modeling of constitutive equations is provided as well as solved examples in engineering applications. A wide range of materials that engineers may encounter are covered, including metals, composites, ceramics, polymers, biomaterials, and nanomaterials. The internationally r…
With global urbanization rapidly rising and the increasing need of high-quality built environments, the requirement of achieving improved sound quality, both for outdoor and indoor environments, has received a lot of attention. This Special Issue collection reflects the current state of the art, with 12 papers covering environmental acoustics; the influence of soundscapes on people’s behavior…
The interplay between host and pathogen is a complex co-evolutionary battle of surveillance and evasion. The pathogen continuously develops mechanisms to subvert the immune response in order to establish infection while the immune system responds with novel mechanisms of detection. Because the majority of Lyme disease pathology is due to an over-exuberant immune response, much research in Borre…