Dynamics of Coupled Structures, Volume 4: Proceedings of the 36th IMAC, A Conference and Exposition on Structural Dynamics, 2018, the fourth volume of nine from the Conference brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of the Dynamics of Coupled Structures, including…
The brain functions within an internal environment that is determined and controlled by morphological structures and cellular mechanisms present at interfaces between the brain and the rest of the body. In vertebrates these interfaces are across cerebral blood vessels (blood-brain barrier) choroid plexuses (blood-cerebrospinal fluid barrier) and pia-arachnoid. There is a CSF-brain barrier in th…
Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance. Hair cells can be damaged due to such factors as agin g, ototoxic chemicals, acoustic trauma, infection, or genetic factors. Loss of hese hair cells lead to deficits in hea…
The formation of human memories involves a series of complicated biochemical processes many of which are not fully understood. However, recent data implicate several families of transcription factors that appear critically important in the regulation of memory. For example, CREB, NF-kB, AP-1, Egr, and C/EBP ...The formation of human memories involves a series of complicated biochemical processe…
The immune system detects "danger", through a series of what we now call damage associated molecular pattern molecules (DAMPs), working in concert with both positive and negative signals derived from other tissues. DAMPS also known as alarmins, are molecules released by stressed cells undergoing necrosis that act as endogenous danger signals to promote and exacerbate the immune and inflammatory…
Recent advances in computer technologies and research now enable to simulate realistic social interaction thanks to the use of increasingly complex computer models. Virtual agents reproducing both human appearance and expressive behaviors are now available for supporting affective interactions with users. Two deeply intertwined fields of knowledge already benefit from such innovations concernin…
Family involvement characterizes a large number of firms around the world and is thought to significantly impact their strategies, behavior, and performance. Family involvement occurs when a family exerts control over the firm through ownership and management. When family involvement leads to intentions to pursue particularistic goals and strategies, controlling families are more likely to exer…
Supercomputing facilities are becoming increasingly available in neuroscience, predominantly for simulating the dynamics of electrical activity propagating through neuronal circuits. On today's most advanced supercomputers, large-scale models can be simulated with up to a billion of neurons. However, merely further increasing the number of neurons and synapses will not be sufficient to create b…
Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this open access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is an ideal reference for general ophthalmologists, surgeons, fellows and trainees around the world who encounter these …
This book focuses on modern methods of oscillation analysis in machines, including cyclic action mechanisms (linkages, cams, steppers, etc.). It presents schematization techniques and mathematical descriptions of oscillating systems, taking into account the variability of the parameters and nonlinearities, engineering evaluations of dynamic errors, and oscillation suppression methods. The major…