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Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondr…
Mitochondrial disease constitutes a complex and heterogeneous group of disorders resulting from a defect in mitochondrial respiratory chain (MRC) enzyme activity. In view of the dual regulation of the MRC, exercised by both the mitochondrial and nuclear genome, mutations in either mitochondrial or nuclear DNA can result in a MRC deficiency. Whilst a single organ can be affected, MRC disorders o…
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- 978-3-03897-241-9
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- 615 CUR
Identification and Characterization of Antimicrobial Peptides with Therapeuti…
Antimicrobial peptides are key defense molecules adopted by all life forms to prevent infection. They also have other beneficial effects such as boosting immune response, anticancer, and wound healing. The antiviral effects of antimicrobial peptides have laid the foundations for developing new agents to combat seasonal Flu, HIV-1, RSV, Zika, and Ebola. This eBook is constructed to systematicall…
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- 978-3-03842-463-5
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- 615 IDE
Molecular Pharmacology and Pathology of Strokes
Stroke, a progressively non-communicable disease, is the second leading cause of death after coronary heart disease in developed countries. The present treatment options for stroke are adapting lifestyle practices, diabetes treatment, drugs, and the management of other factors, but no cure is yet available, despite new insights into molecular and therapeutic targets. Discoveries related to expl…
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- 978-3-03897-542-7
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- 615 MOL m
Transient Receptor Potential (TRP) Channels in Drug Discovery : Old Concepts …
The year 2017 marks the 20th anniversary of the molecular cloning of the long sought-after capsaicin receptor, now known as TRPV1 (Transient Receptor Potential Vanilloid 1). This seminal discovery has opened up a “hot” new field of basic research and launched drug discovery efforts into the large family (by the latest count, 28 mammalian members and 27 in humans) of TRP ion channels. Indeed…
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- 978-3-03842-638-7
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- 615 TRA
Heat Transfer and Pressure Drop in Flow Boiling in Microchannels
This Brief addresses the phenomena of heat transfer and pressure drop in flow boiling in micro channels occurring in high heat flux electronic cooling. A companion edition in the Springer Brief Subseries on Thermal Engineering and Applied Science to “Critical Heat Flux in Flow Boiling in Micro channels,” by the same author team, this volume is idea for professionals, researchers and graduat…
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- 978-3-319-20284-6
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- X, 55
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- 621 SAH h
Heat Transfer Modeling:An Inductive Approach
This innovative text emphasizes a "less-is-more" approach to modeling complicated systems such as heat transfer by treating them first as "1-node lumped models" that yield simple closed-form solutions. The author develops numerical techniques for students to obtain more detail, but also trains them to use the techniques only when simpler approaches fail. Covering all essential methods offered i…
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- 978-3-319-14513-6
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- XVIII, 516
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- 621 SID e
Global Business Strategy : A Systems Approach
The greatest dilemma facing the author of a textbook on international business strategy is estimating readers' knowledge of the domain. Should the author assume that the student already comprehends such subjects as international economics, international trade, and international finance? Or should the book deal extensively with these subjects before tackling management issues? After over fif…
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- 650 OPE g
Economical Bridge Solutions based on innovative composite dowels and integrat…
This book is an outcome of the research project ECOBRIDGE Demonstration of ECOnomical BRIDGE solutions based on innovative composite dowels and integrated abutments RFCS CT 2010-00024, which has been co-funded by the Research Fund for Coal and Steel (R.F.C.S.) of the European Community. The main topics of the book are the following: design of integral bridges, innovative composite dowels for th…
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- 9781322171357
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- 620
Problem Solving in Teams and Groups
This textbook covers content relevant to COMS342: Problem Solving in Teams and Groups at the University of Kansas. Content in this textbook is adapted from The Open University, OpenStax, The Noba Project, and Wikipedia. Each chapter presents the source in the top header and each chapter has its own version of the Creative Commons (CC) license, noted at the bottom of the chapter. This book (comm…
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- 658 PIE p
Operations Management
Global competition has caused fundamental changes in the competitive environment of manufacturing industries. Firms must develop strategic objectives which, upon achievement, result in a competitive advantage in the market place. However, for almost all manufacturing industries, an increased productivity and better overall efficiency of the production line are the most important goals. Most ind…
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- 658 FEL o
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