Mitochondrial disease constitutes a complex and heterogeneous group of disorders resulting from a defect in mitochondrial respiratory chain (MRC) enzyme activity. In view of the dual regulation of the MRC, exercised by both the mitochondrial and nuclear genome, mutations in either mitochondrial or nuclear DNA can result in a MRC deficiency. Whilst a single organ can be affected, MRC disorders o…
With global urbanization rapidly rising and the increasing need of high-quality built environments, the requirement of achieving improved sound quality, both for outdoor and indoor environments, has received a lot of attention. This Special Issue collection reflects the current state of the art, with 12 papers covering environmental acoustics; the influence of soundscapes on people’s behavior…
The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity and (3) bi…
Going green, green business, and sustainable business are topics on everyone’s mind. But what does all this mean exactly? A Primer on Sustainable Business answers that question and provides an introduction to the basics you need to know. We begin with an understanding of the background of the concept of sustainability and how it applies to the business world. In 1987, the Brundtland Commissi…
You are probably asking yourself the question, "When and where will I use statistics?" If you read any newspaper, watch television, or use the Internet, you will see statistical information. There are statistics about crime, sports, education, politics, and real estate. Typically, when you read a newspaper article or watch a television news program, you are given sample information. With this …
this Handbook of Experimental Pharmacology on “High Density Lipoproteins – from biological understanding to clinical exploitation” contributing authors (members of COST Action BM0904/HDLnet) summarize in more than 20 chapters our current knowledge on the structure, function, metabolism and regulation of HDL in health and several diseases as well as the status of past and ongoing attempts …
Moral dilemmas are a pervasive feature of working life. Moral Reasoning at Work offers a fresh perspective on how to live with them. How do we cope with situations where no matter what we decide to do, something will be wrong? How do we live with the moral dissonance between what we are tempted to do and what is in line with our moral convictions? What can organizations do to establish a founda…
Welcome to Human Anatomy and Physiology, an OpenStax College resource. We created this textbook with several goals in mind: accessibility, customization, and student engagement—helping students reach high levels of academic scholarship. Instructors and students alike will find that this textbook offers a thorough introduction to the content in an accessible format.