The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of …
This title provides a point-of-care reference for busy clinicians who need the best evidence based answers to patient questions at their fingertips. Additionally, it guides clinicians through the complicated therapeutic management of IBD including drug initiation, medications side effects and complications, therapeutic level monitoring and accurate disease monitoring. Lastly, it addresses speci…
This book reports significant progress of scientific research on horseshoe crabs, including aspects of evolution, genetics, ecology, population dynamics, general biology and physiology, within the recent 10 years. It also highlights the emerging issues related to world-wide conservation threats, status and needs. The contributions in this book represent part of an ongoing global effort to incre…
This unifying theme of this book-with sections on mechanisms of defense and neuropathogenesis, neurological diseases, infections of the nervous system, neuropharmacology, and novel therapies-is interactions of the immune and nervous systems. It also discusses the role of inflammation as a key mediator of different brain disorders. There have been significant scientific advances in the multidisc…
Challenges in Mechanics of Time-Dependent Materials, Volume 2 of the Proceedings of the 2015SEM Annual Conference& Exposition on Experimental and Applied Mechanics, the second volume of nine from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Experime…
The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular disease, Alzheimer’s disease, ovarian aging, dietary and endogenous anti-oxidants in m…
This book provides a concise introduction to important aspects of contemporary innovation policy, with particular emphasis on its impact on economic growth and development. It addresses a non-specialist audience interested in quickly building background knowledge, getting familiar with the terminology, and understanding core concerns and debates in this area of policy. The book has its origins …
This book documents recent advances in the field of modeling, simulation, control, security and reliability of Cyber- Physical Systems (CPS) in power grids. The aim of this book is to help the reader gain insights into working of CPSs and understand their potential in transforming the power grids of tomorrow. This book will be useful for all those who are interested in design of cyber-physical …
This contributed volume draws a vital picture of the health care sector, which, like no other is affected by technology push and stakeholder pull. Innovative product and service solutions emerge, which have to integrate different stakeholders’ interests. This book studies current challenges in health care management from different perspectives. Research articles analyze the situation in the h…
The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laborat…