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Studies on Psychiatric Disorders

This authoritative volume reviews clinical, pathophysiological and therapeutic aspects of oxidative and nitrosative stress in different psychiatric disorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeutic aspects. Together, these chapters present the environmental, genetic and neurodevelopmental factors in the generation of oxidative stress in psychiatric disorders, with particular emphasis on the biochemical changes associated with oxidative stress in dopaminergic and glutamate neurotransmission as well as mitochondrial dysfunction in the brain and peripheral cells. Through an investigation of glutamic acid decarboxylase (GAD) abnormalities in schizophrenia, the book provides a coherent framework to account for the impact of oxidative stress on pathological phenomena ranging from cellular to cognitive and clinical aspects. It describes biomarkers of oxidative damage, the role of oxidative stress in numerous abnormalities of biochemical pathways in the pathophysiology of schizophrenia, the development of new investigative techniques, specially neuroimaging, and studies of apoptotic pathways that seem to prove neurodegenerative and neurodevelopmental theories.

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Detail Information
Series Title
Oxidative Stress in Applied Basic Research and Clinical Practice
Call Number
-
Publisher
Cham : Springer.,
Collation
XX, 596
Language
English
ISBN/ISSN
978-1-4939-0440-2
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
Biomedical and Life Sciences
Specific Detail Info
-
Statement of Responsibility
Other Information
Cataloger
Jemadi
Source
https://link.springer.com/content/pdf/10.1007/978-1-4939-0440-2.pdf?pdf=button
Validator
-
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