Text

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

---

The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems.

---

Availability

No copy data

Detail Information

Series Title

Springer Theses

Call Number

-

Publisher

: ., 2016

Collation

XIII

Language

English

ISBN/ISSN

978-3-319-80758-4

Classification

NONE

Content Type

-

Media Type

-

Carrier Type

-

Edition

1

Subject(s)

Cell Biology
Neuroscience
Biomedical Engineering and Bioengineering
Electronics and Microelectronics
Instrumentation

Specific Detail Info

-

Statement of Responsibility

Springer Theses

Other Information

Cataloger

ULAN

Source

-

Validator

Taufik

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment