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The Functional Nucleus

This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.

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Detail Information
Series Title
-
Call Number
-
Publisher
Springer Cham : Springer Cham.,
Collation
VI, 513
Language
English
ISBN/ISSN
978-3-319-38882-3
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
-
Edition
-
Subject(s)
Molecular Genetics
Specific Detail Info
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Statement of Responsibility
Other Information
Cataloger
Jemadi
Source
https://link.springer.com/content/pdf/10.1007/978-3-319-38882-3.pdf?pdf=button
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