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The Genetics of Type 2 Diabetes and Related Traits

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The first section explores genome-wide association studies, the extension of this method to less accessible phenotypes and the arrival of next-generation sequencing. A further section goes beyond genetics to illustrate how other data sources can help interpret genetic data, such as leveraging population diversity, the correlation of genetic associations with physiological measurements, gene expression modulation, environmental factors and our microbial commensals. The third section describes advances in elucidating the complex path from association to function using in-depth sequencing and functional studies of the cellular and molecular effects of genes in the loci identified by genetics. The final section links our current understanding with clinically relevant questions, such as prediction, interactions with drugs or nutrients, and disease prevention, and paints a realistic but hopeful vision of the future.

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دستیابی

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Detail Information

سلسلہ عنوان

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حوالہ نمبر

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ناشر

Springer Cham : Springer Cham., 2016

Collation

XI, 576

زبان

English

آئی ایس بی این/آئی ایس ایس این

978-3-319-01574-3

درجہ بندی:

NONE

Content Type

text

Media Type

computer

Carrier Type

-

شامل کریں

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موضوع(s)

Medical Genetics, Diseases, Human Physiology

مخصوص تفصیل معلومات

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Statement of Responsibility

Editors Jose C. Florez

Other Information

Cataloger

Jemadi

Source

https://link.springer.com/content/pdf/10.1007/978-3-319-01574-3.pdf?pdf=button

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Other version/related

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