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The Immune System in Space: Are we prepared?

Several limiting factors for human health and performance in microgravity have been clearly identified as an unacceptable risk for long-term and interplanetary flights. Serious concerns arose whether spaceflight-associated immune system dysfunction ultimately precludes the expansion of human presence beyond Earth's orbit. The immune system has undergone many evolutionary steps to cope with a new and changing environment, but `space` has not been evolutionary experienced before. Through endocrine orchestration of cell functions, cell to cell communications and intracellular mechanisms the human body and his immune system have an enormous capacity to adapt and react to altered environmental conditions. Thus, the special sensitivity to altered gravity renders the immune system an ideal biological model system to understand if and how gravity on Earth is required for the normal function of cells and cellular networks. It is one of the most fundamental challenges to find out, if our organism and our cellular machinery are able to live and to adequately perform without the gravity field of Earth.

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Detail Information
Series Title
SpringerBriefs in Space Life Sciences
Call Number
-
Publisher
Springer Cham : Springer Cham.,
Collation
XVII, 127
Language
English
ISBN/ISSN
978-3-319-41466-9
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
-
Edition
-
Subject(s)
Aerospace Technology and Astronautics
Specific Detail Info
-
Statement of Responsibility
Other Information
Cataloger
Jemadi
Source
https://link.springer.com/content/pdf/10.1007/978-3-319-41466-9.pdf?pdf=button
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