Text

The Long and Short Non-coding RNAs in Cancer Biology

---

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

---

Availability

No copy data

Detail Information

Series Title

Advances in Experimental Medicine and Biology

Call Number

-

Publisher

Singapore : Springer Singapore., 2016

Collation

VIII, 458

Language

English

ISBN/ISSN

978-981-10-1498-7

Classification

NONE

Content Type

text

Media Type

computer

Carrier Type

-

Edition

-

Subject(s)

Cancer Biology, Cell Biology

Specific Detail Info

-

Statement of Responsibility

Editors: Erwei Song

Other Information

Cataloger

Jemadi

Source

https://link.springer.com/content/pdf/10.1007/978-981-10-1498-7.pdf?pdf=button

Validator

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment