Image of The Mechanobiology of Obesity and Related Diseases
Bookmark Share

Text

The Mechanobiology of Obesity and Related Diseases

There appears to be an interaction between the loading states in tissues and cells and these chronic conditions, as well as with factors such as age, gender and genetics of the individual. Bioengineering has made key contributions to this research field in providing technologies for cell biomechanics experimentation, microscopy and image processing, tissue engineering and multi-scale, multi-physics computational modeling. Topics at the frontier of this field of study include: the continuous monitoring of cell growth, proliferation and differentiation in response to mechanical factors such as stiffness of the extracellular matrix (ECM) and mechanical loads transferred through the ECM; mechanically-activated signaling pathways and molecular mechanisms; effects of different loading regimes and mechanical environments on differentiation fates of mesenchymal stem cells (MSCs) into myogenic and osteogenic versus adipogenic lineages; the interactions between nutrition and mechanotransduction; cell morphology, focal adhesion patterns and cytoskeletal remodeling changes in adipogenesis; activation of receptors related to diabetes by mechanical forces; brown and white adipose plasticity and its regulation by mechanical factors.

Availability

No copy data

Detail Information
Series Title
Studies in Mechanobiology, Tissue Engineering and Biomaterials
Call Number
-
Publisher
Springer Cham : Springer Cham.,
Collation
X, 296
Language
English
ISBN/ISSN
978-3-319-09336-9
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
-
Edition
-
Subject(s)
Biomaterials
Specific Detail Info
-
Statement of Responsibility
Other Information
Cataloger
Jemadi
Source
https://link.springer.com/content/pdf/10.1007/978-3-319-09336-9.pdf?pdf=button
Validator
-
Other version/related

No other version available

File Attachment
Comments
You must be logged in to post a comment