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Image of Optimized Response-Adaptive Clinical Trials
Sequential Treatment Allocation Based on Markov Decision Problems
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Optimized Response-Adaptive Clinical Trials Sequential Treatment Allocation Based on Markov Decision Problems

ONDRA, Thomas - Personal Name;

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.


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Detail Information
Series Title
-
Call Number
-
Publisher
Springer Fachmedien Wiesbaden : Springer Spektrum Wiesbaden., 2015
Collation
-
Language
English
ISBN/ISSN
978-3-658-08344-1
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
Analysis
Probability Theory
Computational Mathematics and Numerical Analysis
Specific Detail Info
-
Statement of Responsibility
Thomas Ondra
Other Information
Cataloger
Yudi
Source
-
Validator
-
Other version/related

No other version available

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  • Optimized Response-Adaptive Clinical Trials Sequential Treatment Allocation Based on Markov Decision Problems
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