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IgE Antibodies: Generation and Function

LAFAILLE, Juan J., - Personal Name; AFAILLE, Maria A. Curotto de L - Personal Name;

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.


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Detail Information
Series Title
-
Call Number
616 IGE
Publisher
: ., 2015
Collation
IX, 152
Language
English
ISBN/ISSN
978-3-319-13724-7
Classification
616
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
Antibodies
Specific Detail Info
-
Statement of Responsibility
Juan J. Lafaille, Maria A. Curotto de Lafaille editor
Other Information
Cataloger
Khusnun
Source
-
Validator
-
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No other version available

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  • IgE Antibodies: Generation and Function
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