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Formulating Poorly Water Soluble Drugs

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The objective of this volume is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at minimum a working knowledge of each of the abovementioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop

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Detail Information

Series Title

AAPS Advances in the Pharmaceutical Sciences Series

Call Number

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Publisher

Cham : Springer., 2016

Collation

XIV, 779 pages

Language

English

ISBN/ISSN

978-3-319-42609-9

Classification

NONE

Content Type

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Media Type

computer

Carrier Type

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Edition

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Subject(s)

Pharmaceutical Sciences/Technology

Specific Detail Info

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Statement of Responsibility

Robert O. Williams III, Alan B. Watts, Dave A. Miller

Other Information

Cataloger

Jemadi

Source

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Validator

Jemadi

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Journal Volume

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Journal Issue

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