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Inflammatory Disorders

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The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.

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Detail Information

Series Title

-

Call Number

615 INF

Publisher

: ., 2015

Collation

X, 67

Language

English

ISBN/ISSN

978-3-319-10011-1

Classification

615

Content Type

text

Media Type

computer

Carrier Type

online resource

Edition

-

Subject(s)

Pharmacology/Toxicology,

Specific Detail Info

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Statement of Responsibility

Mieczyslaw Pokorski editor

Other Information

Cataloger

Khusnun

Source

-

Validator

-

Digital Object Identifier (DOI)

-

Journal Volume

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Journal Issue

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Subtitle

-

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