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Inflammasome Signaling and Bacterial Infections

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This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.

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Detail Information

Series Title

Current Topics in Microbiology and Immunology

Call Number

610

Publisher

Switzerland : Springer Cham., 2016

Collation

XI, 282

Language

English

ISBN/ISSN

978-3-319-41170-5

Classification

610

Content Type

text

Media Type

computer

Carrier Type

online resource

Edition

1

Subject(s)

Medical Microbiology,

Specific Detail Info

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Statement of Responsibility

Steffen Backert

Other Information

Cataloger

Khusnun

Source

-

Validator

Taufik

Digital Object Identifier (DOI)

-

Journal Volume

-

Journal Issue

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Subtitle

-

Parallel Title

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