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Genome Editing

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This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field.

Genome Editing: The Next Step in Gene Therapy, the latest volume in the American Society of Gene and Cell Therapy series, deftly illuminates the potential of genetic engineering technology to eradicate today’s deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology.

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Detail Information

Series Title

Advances in Experimental Medicine and Biology

Call Number

570

Publisher

New York : Springer New York, NY., 2016

Collation

Biologi

Language

English

ISBN/ISSN

978-1-4939-3509-3

Classification

NONE

Content Type

text

Media Type

computer

Carrier Type

online resource

Edition

1

Subject(s)

Genetics
Human Genetics

Specific Detail Info

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Statement of Responsibility

Toni Cathomen

Other Information

Cataloger

Suwardi

Source

https://link.springer.com/book/10.1007/978-1-4939-3509-3

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