Synthesis and Characterization of New Racemic α-Heterocyclic α,α-Diaminoester and α,α-Diamino Acid Carboxylic: 2-Benzamido-2-[(Tetrahydro-Furan-2-Ylmethyl)Amino]Acetate and 2-Benzamido-2-[(Tetrahydro-Furan-2-Ylmethyl)Amino] Acetic Acid

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https://mts.intechopen.com/articles/show/title/synthesis-and-characterization-of-new-racemic-heterocyclic-diaminoester-and-diamino-acid-carboxylic-We reported here the synthesis of new α,α-diaminoester and α,α-diamino acid derivatives, as 2-benzamido-2-[(tetrahydro-furan-2-ylmethyl)amino] acetic acid through alkaline hydrolysis reaction of corresponding N-benzoylated methyl α,α-diamino ester. The α,α-diaminoester derivative was synthesized by nucleophilic substitution of methyl α-azido glycinate N-benzoylated with 2-tetrahydrofuran-2-ylmethan-amine. The structure of these products were established on the basis of NMR spectroscopy (1H, 13C), and MS data.https://creativecommons.org/licenses/by/3.0/en

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: IntechOpen,., 2022-05-11.

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English

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