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Journey from Cognition to Brain to Gene: Perspectives from Williams Syndrome

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A blueprint for the investigation of neurodevelopmental disorders, this book presents the work of a team of scientists using a multidisciplinary, integrated approach to link genes with human behavior. Using Williams syndrome as a model, leading researchers in neuroanatomy, neurocognition, neurophysiology, and molecular genetics have built bridges between disciplines to link higher cognitive functions, their underlying neurobiological bases, and their molecular genetic underpinnings. One of the book's many strengths is that the scientists from each discipline studied the same individuals with Williams syndrome. As the book shows, Williams syndrome is a fascinating disorder because of the "peaks and valleys" among cognitive domains: severe intellectual deficits but remarkably spared and effusive language; specific impairment in spatial construction but great strength in face processing and sociability. By capitalizing on these dissociations in higher cognitive functioning, the book provides a model for the study of brain-behavior relationships as well as for the mapping of brain and behavior phenotypes to the genome and beyond. Contributors Ralph Adolphs, Twyla Alvarez, Lawrence Appelbaum, Ursula Bellugi, Dennis Burian, Xiao-Ning Chen, Michael Chiles, Stephan Eliez, Albert Galaburda, Hanao Hirota, Wendy Jones, Julie Korenberg, Zona Lai, Liz Lichtenberger, Alan Lincoln, Rumiko Matsuoka, Debra Mills, Helen Neville, Judy Reilly, Allan Reiss, Bruce Roe, Marie St. George, J. Eric Schmidtt, Erica Straus.

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Detail Information

Series Title

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Call Number

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Publisher

Williams syndrome;Williams syn : Cambridge, Mass. : MIT Press,., 2001

Collation

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Language

English

ISBN/ISSN

9780262287395

Classification

NONE

Content Type

text

Media Type

computer

Carrier Type

online resource

Edition

1

Subject(s)

NEUROSCIENCE/General

Specific Detail Info

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Statement of Responsibility

Ursula Bellugi, Marie St. George

Other Information

Cataloger

Suwardi

Source

https://direct.mit.edu/books/edited-volume/2850/Journey-from-Cognition-to-Brain-to

Validator

Suwardi

Digital Object Identifier (DOI)

https://doi.org/10.7551/mitpress/4036.001.0001

Journal Volume

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Journal Issue

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