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The Pangenome = Diversity, Dynamics and Evolution of Genomes

Hervé Tettelin - Personal Name; Duccio Medini - Personal Name;

This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications.

The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes.

The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory.

Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.


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1706012025
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Detail Information
Series Title
-
Call Number
-
Publisher
: Springer Cham., 2020
Collation
XIV, 307 hlm; ill., lamp.,
Language
English
ISBN/ISSN
9783030382810
Classification
-
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
1
Subject(s)
Evolutionary Biology
Genetics and Genomics

Microbial Genetics and Genomics
Genetics and Population Dynamics
Specific Detail Info
This open access book covers the fundamental impacts of intra-species genomic diversity Focuses on the evolutionary biology of pan-genomes Elaborates on computational strategies and mathematical models for pan-genome analysis Discusses cutting-edge concepts such as pan-phenomes and pan-epigenomes
Statement of Responsibility
Hervé Tettelin, Duccio Medini
Other Information
Cataloger
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Source
https://link.springer.com/book/10.1007/978-3-030-38281-0
Validator
ida
Digital Object Identifier (DOI)
https://doi.org/10.1007/978-3-030-38281-0
Journal Volume
-
Journal Issue
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Subtitle
-
Parallel Title
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No other version available

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