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Adrenal Cortex: From Physiology to Disease

The adrenal gland plays essential roles in the control of body homeostasis, stress and immune responses. The adrenal cortex represents up to 90% of the gland and is specialised in the production of mineralocorticoids, glucocorticoids and adrenal androgens. This production is tightly coordinated and results from a unique zonal organisation. Although our knowledge of the molecular mechanisms controlling adrenal steroidogenesis is quite extensive, for decades, the mechanisms of adrenal cortex development, cellular homeostasis and renewal have remained elusive. The advent of new high-throughput technologies and sophisticated genetic approaches has brought tremendous progress in our understanding of how the adrenal cortex achieves and maintains its particular organisation. The aim of this Frontiers in Endocrinology Topic is to provide readers with a snapshot of our current knowledge on adrenal physiology and how deregulations of these processes result in adrenal diseases. This includes but is not limited to, basic research on adrenal development, cell lineage identification, progenitor cells, tissue renewal, control of differentiation and zonation and clinical research on the identification of disease-related genes.

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Detail Information
Series Title
Frontiers Research Topics,
Call Number
-
Publisher
www.frontiersin.org : Frontiers Media SA.,
Collation
oer.unej.ac.id
Language
English
ISBN/ISSN
9782889199198
Classification
-
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
Medicine
Nursing
Specific Detail Info
-
Statement of Responsibility
Other Information
Cataloger
-
Source
https://directory.doabooks.org/handle/20.500.12854/40168
Validator
Suwardi
Digital Object Identifier (DOI)
10.3389/978-2-88919-919-8
Journal Volume
-
Journal Issue
-
Subtitle
-
Parallel Title
-
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