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Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression


Abstract
This book introduces systems epidemiology, which is a new scientific discipline borne by novel technologies. These have opened up the potential for studies of temporal changes in the carcinogenic process and the response of the immune system, all measured as functional genomics: gene expression, microRNA and methylation. Systems epidemiology is an integrated approach based on epidemiological methods with biobanks designed for studies of the trajectories or curves of functional genomics moving from before diagnosis, at diagnosis and postdiagnostic. It demands new epidemiological designs, the globolomic one, new statistical methods for description and analyses of time changes and incorporating basic knowledge from reductionist experiments and clinical outcomes including molecular biomarkers of cancer tissue and normal tissues.


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Detail Information
Series Title
-
Call Number
-
Publisher
: ., 2020
Collation
-
Language
ISBN/ISSN
788215041193
Classification
NONE
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
-
Specific Detail Info
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Statement of Responsibility
Eiliv Lund
Other Information
Cataloger
Heri
Source
-
Validator
-
Digital Object Identifier (DOI)
https://directory.doabooks.org/handle/20.500.12854/40384
Journal Volume
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Journal Issue
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Subtitle
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Parallel Title
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  • Advancing Systems Epidemiology in Cancer - Exploring Trajectories of Gene Expression
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