Text

Advances in Single Molecule, Real-Time (SMRT) Sequencing

---

PacBio’s single-molecule real-time (SMRT) sequencing technology offers important advantages over the short-read DNA sequencing technologies that currently dominate the market. This includes exceptionally long read lengths (20 kb or more), unparalleled consensus accuracy, and the ability to sequence native, non-amplified DNA molecules. From fungi to insects to humans, long reads are now used to create highly accurate reference genomes by de novo assembly of genomic DNA and to obtain a comprehensive view of transcriptomes through the sequencing of full-length cDNAs. Besides reducing biases, sequencing native DNA also permits the direct measurement of DNA base modifications. Therefore, SMRT sequencing has become an attractive technology in many fields, such as agriculture, basic science, and medical research. The boundaries of SMRT sequencing are continuously being pushed by developments in bioinformatics and sample preparation. This book contains a collection of articles showcasing the latest developments and the breadth of applications enabled by SMRT sequencing technology.

---

Availability

No copy data

Detail Information

Series Title

-

Call Number

-

Publisher

: MDPI - Multidisciplinary Digital Publishing Institute., 2019

Collation

-

Language

English

ISBN/ISSN

9783039217014

Classification

NONE

Content Type

text

Media Type

computer

Carrier Type

online resource

Edition

1

Subject(s)

-

Specific Detail Info

-

Statement of Responsibility

-

Other Information

Cataloger

Hasan

Source

https://directory.doabooks.org/handle/20.500.12854/40355

Validator

-

Digital Object Identifier (DOI)

10.3390/books978-3-03921-701-4

Journal Volume

-

Journal Issue

-

Subtitle

-

Parallel Title

-

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment