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Chapter 12 Modelling Threshold-Dependent Gene Drives: a Case Study Using Engineered Underdominance

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In this chapter, we outline a range of modelling approaches that have been used to demonstrate the key characteristics of this approach, including threshold introduction frequencies, reversibility, spatial limitation and robustness to mutation/resistance. We then go on to discuss alternative configurations based on the use of sex-specific components and their effect on introduction thresholds. We conclude with a discussion on the cycle of information between mathematical models and experimental data along with a range of areas for future modelling that will be important in providing information on the anticipated effects of these systems when released into target populations.

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: Cabi., 2022

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Language

English

ISBN/ISSN

9781800621152, 9781800621176

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NONE

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text

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computer

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1

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Hasan

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https://directory.doabooks.org/handle/20.500.12854/101467

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Digital Object Identifier (DOI)

10.1079/9781800621176.0012

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