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Mitochondrial Dysfunction in Ageing and Diseases

The past decade has witnessed an explosion of knowledge regarding how mitochondrial dysfunction may translate into ageing and disease phenotypes, as well as how it is modulated by genetic and lifestyle factors. Impairment of the mitochondria may be caused by mutations or deletions in nuclear or mitochondrial DNA. Hallmarks of mitochondrial dysfunction include decreased ATP production, decreased mitochondrial membrane potential, swollen mitochondria, damaged cristae, increased oxidative stress, and decreased mitochondrial DNA copy number.

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Detail Information
Series Title
-
Call Number
616 MIT
Publisher
Basel : MDPI - Multidisciplinary Digital Publishing Institute.,
Collation
-
Language
English
ISBN/ISSN
978-3-03842-252-5
Classification
616
Content Type
text
Media Type
computer
Carrier Type
online resource
Edition
-
Subject(s)
Diseases
Specific Detail Info
-
Statement of Responsibility
Other Information
Cataloger
maya
Source
-
Validator
maya
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