Local anesthetics are being increasingly applied in different surgeries. Lower side effects of neuroaxial anesthesia, regional anesthesia, and field block, in comparison to general anesthesia (volatile and intravenous agents), are the main reasons why physicians prefer to conduct surgeries under local anesthesia, especially in outpatient and day care surgeries. It is important to emphasize the …
Though the number of infants born with heart disease each year is relatively small (approximately 1% of the population), it is still a substantial issue worthy of investigation, which is why this Special Issue focuses on congenital heart disease in both children and adults. Advances in the treatment of such malformations have led to increased life spans for this population. Consequently, today,…
In this Special Issue, our aim was to collect studies on clinical pharmacology and pharmacy of antimicrobial agents from both human and veterinary medicine as the complex problem of AMR requires actions taken within the One Health approach that involve both fields. Studies covered here are about new or optimized usage of already authorized antimicrobials, as well as discoveries about new agents…
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researcher…
The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. This book presents Pharmacogenetic examples from a broad spectru…
Terapi seluler (cellular therapies) telah merevolusi bidang onkologi modern, mengubah paradigma pengobatan kanker dari kemoterapi konvensional menuju pendekatan imunoterapi presisi berbasis sel hidup. Buku ini menyajikan tinjauan komprehensif mengenai prinsip dasar, desain rekayasa genetik, serta aplikasi klinis berbagai modalitas terapi seluler dalam mengatasi keganasan hematologi maupun tumor…
Tinjauan komprehensif literatur ilmiah tentang kemungkinan manfaat CBD, yang menjelaskan temuan dari studi klinis praklinis dan manusia. CBD (cannabidiol), senyawa non-toksik yang berasal dari tanaman ganja, dapat ditemukan dalam produk mulai dari losion dan smoothie hingga permen karet kunyah dan makanan hewan peliharaan. Ini telah dipromosikan-tetapi tidak selalu divalidasi secara ilmiah-seba…
Pemberian Obat dan Imunoterapi yang Ditingkatkan dengan Kavitasi adalah area yang berkembang pesat yang telah didukung dalam beberapa tahun terakhir oleh pengembangan metode yang memanfaatkan aktivitas gelembung yang dirangsang oleh ultrasound, yang dikenal sebagai kavitasi. Ketika dikontrol dengan benar, kavitasi dapat membantu mengatasi hambatan fisik terhadap pemberian obat sambil memberikan…
Di loteng institut botani Universitas Georg-August di Gottingen, koleksi farmakognostik disimpan selama lebih dari enam puluh tahun, dikemas dalam sekitar 50 kotak: dokumen disiplin ilmu yang diwakili oleh institut tersebut hingga tahun 1938. Koleksinya terdiri dari sekitar 8.000 sampel dan benda dari materia medica dari abad ke-19 dan awal abad ke-20; dengan demikian, ini adalah salah satu dar…
If marine organisms are to persist through the Anthropocene, they will need to be resilient, but what is resilience, and can resilience of marine organisms build within a single lifetime or over generations? The aim of this review is to evaluate the resilience capacity of marine animals in a time of unprecedented global climate change. Resilience is the capacity of an ecosystem, society, or org…