Rhododendrol (RD) is a naturally occurring phenolic compound found in many plants. Tyrosinase (Ty) converts RD to RD-catechol and subsequently RD-quinone via two-step oxidation reactions, after which RD-melanin forms spontaneously from RD-quinone. RD is cytotoxic in melanocytes and lung cancer cells, but not in keratinocytes and fibroblasts.
The convergence of big data and geospatial computing has brought challenges and opportunities to GIScience with regards to geospatial data management, processing, analysis, modeling, and visualization. This special issue highlights recent advancements in integrating new computing approaches, spatial methods, and data management strategies to tackle geospatial big data challenges and meanwhi…
The availability of powerful non-invasive neuroimaging techniques has given rise to various studies that aim to map the human brain. These studies focus on not only finding brain activation signatures but also on understanding the overall organization of functional communication in the brain network. Based on the principle that distinct brain regions are functionally connected and continuou…
Machine learning models can automatically discover biomedical research trends and promote the dissemination of information and knowledge. Text feature representation is a critical and challenging task in natural language processing. Most methods of text feature representation are based on word representation. A good representation can capture semantic and structural information.
Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand …
The recent development of underground space technology makes underground space a potential and feasible solution to climate change, energy shortages, the growing population, and the demands on urban space. Advances in material science, information technology, and computer science incorporating traditional geotechnical engineering have been extensively applied to sustainable and resilient underg…
Physical limitations on wireless communication channels impose huge challenges to reliable communication. Bandwidth limitations, propagation loss, noise and interference make the wireless channel a narrow pipe that does not readily accommodate rapid flow of data. Thus, researches aim to design systems that are suitable to operate in such channels, in order to have high performance quality of se…
We propose in this paper two heuristic strategies to solve the regenerator placement problem (RPP) in translucent networks under dynamic traffic. The heuristics are based on both the forecast of the offered load and estimates of blocking probabilities in the network nodes
This book, edited by the Intech committee, combines several hotly debated topics in science, engineering, medicine, information technology, environment, economics and management, and provides a scholarly contribution to its further development. In view of the topical importance of, and the great emphasis placed by the emerging needs of the changing world, it was decided to have this special boo…
The concept of synergistic effects has been widely applied in many scientific fields such as in biomedical science and material chemistry, and has further attracted interest in the fields of both synthesis and application of nanomaterials. In this paper, we report the synthesis of long-wavelength emitting silicon quantum dots based on a one-step hydrothermal route with catechol (CC) and sodi…